The Autism Protein Ube3A/E6AP Remodels Neuronal Dendritic Arborization via Caspase-Dependent Microtubule Destabilization
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چکیده
منابع مشابه
Cortactin-binding protein 2 increases microtubule stability and regulates dendritic arborization.
Neurons are characterized by subcellular compartments, such as axons, dendrites and synapses, that have highly specialized morphologies and biochemical specificities. Cortactin-binding protein 2 (CTTNBP2), a neuron-specific F-actin regulator, has been shown to play a role in the regulation of dendritic spine formation and their maintenance. Here, we show that, in addition to F-actin, CTTNBP2 al...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2017
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1511-17.2017